英國倫敦大學學院(University College London; UCL)惠康信託基金神經影像中心(Wellcome Trust Centre for Neuroimaging)以及紐卡斯爾大學的研究人員運用功能性核磁共振顯像(functional magnetic resonance imaging, fMRI),檢驗 13 位自願受試者的腦部如何對一系列音頻不同的聲響作反應。受試者聆聽儀器發出的聲響後,從最令人不舒服(例如:用刀子劃玻璃瓶)到讓人感覺舒適(例如:水流聲)進行評分。如此一來,研究人員便能研究腦部對不同型態聲音的反應。
裸蓋菇素的研究引起了美國中央情報局 CIA 的注意,不過不是因為什麼違法亂紀的問題,而是他們⋯⋯也想「瞭解更多」!1950年代 CIA 有項名為 MK-Ultra 2 的精神控制計畫,希望找到一些可以作為吐真劑、審訊和行為操縱工具的潛力藥物。他們的實驗藥物包括裸蓋菇素、迷幻藥 LSD、嗎啡、海洛因、一種萃取自仙人掌的致幻劑麥斯卡林等,並在監獄、醫院、學校,甚至從巧立名目的慈善基金會裡招募試驗對象。3
Single-dose psilocybin for treatment-resistant obsessive-compulsive disorder: A case report – PMC (nih.gov)↩︎
Single-dose psilocybin-assisted therapy in major depressive disorder: a placebo-controlled, double-blind, randomised clinical trial – eClinicalMedicine (thelancet.com)↩︎
Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder: A Randomized Clinical Trial | Substance Use and Addiction Medicine | JAMA Psychiatry | JAMA Network↩︎
Long-term Follow-up of Psilocybin-facilitated Smoking Cessation – PMC (nih.gov)↩︎
Frontiers | Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey (frontiersin.org)↩︎
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